Skip to main content

CREDENCE - Primary renal outcome benefit demonstrated with Canagliflozin 100mg . Published in NEJM April 14th 2019

In this double-blind, randomized trial, 'abstract of published paper' assigned patients with type 2 diabetes and

albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor,

at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular

filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area