ABCD nationwide audits of new diabetes therapies

Dr Bob Ryder¹

¹City Hospital, Birmingham, UK

“The NHS is open” - Diabetes UK urges parents to be

4Ts aware during lockdown

The guidance in this document is based on experience from UK centres with the greatest experience of looking after patients with COVID-19 disease and will be updated as more evidence becomes available.  The document provides helpful algorithms for management and treatment.

Caution - COVID-19 infection in people with or without previously recognised diabetes increases the risk of the EMERGENCY states of hyperglycaemia with ketones, Diabetic KetoAcidosis (DKA) and Hyperosmolar Hyperglycaemic State (HHS)

Combined liraglutide-insulin therapy is associated with metabolic improvement and insulin dose reduction in commonly prescribed insulin regimens

Piya Sen Gupta¹, Ken Y Thong², Christopher Walton³, Robert EJ Ryder¹, on behalf of ABCD liraglutide audit contributors

¹City Hospital, Birmingham, UK

²Rockingham General Hospital, Perth, Australia

³Hull Royal Infirmary, Hull, UK

NICE guidelines versus clinical practice – GLP-1 receptor agonists in type 2 diabetes: the ABCD nationwide audits

KY Thong¹, P Sen Gupta², ML Cull², KA Adamson³, DS Dove⁴, SV Rowles⁵, S Tarpey⁵, C Duncan⁶ , J Chalmers⁶, R Harper⁷, P McDonald⁷, U Brennan⁷, C Walton⁸, REJ Ryder² on behalf of the ABCD Nationwide exenatide^* and liraglutide^† audit contributors

The efficacy of exenatide and liraglutide among South Asians in the Association of British Clinical Diabetologists nationwide audits

KY Thong¹, P Sen Gupta^1,2, REJ Ryder¹

¹Department of Diabetes, City Hospital, Birmingham, UK

²Diabetes Research Group, King’s College, London, UK

Does Liraglutide Therapy Affect the Metabolic Response in Patients with An Elevated Alanine Aminotransferase and Type 2 Diabetes Mellitus?: The Association of British Clinical Diabetologists (ABCD) Nationwide Liraglutide Audit

Sen Gupta P¹, Thong KY¹, Armstrong M², Newsome PN², Winocour P³, Ryder REJ¹

¹City Hospital, Birmingham, UK

²University of Birmingham, Birmingham, UK

³Queen Elizabeth Hospital, Welwyn Garden City, UK

Liraglutide and acute pancreatitis in the Association of British Clinical Diabetologists (ABCD) nationwide liraglutide audit

Ryder REJ¹, Thong KY², Blann A¹, Phillips S³, Barwell N⁴, Kelly C⁴, Semple C⁵, Struthers S⁵, Sen Gupta P¹, on behalf of the ABCD Nationwide Liraglutide Audit contributors

¹City Hospital, Birmingham, UK

²Rockingham General Hospital, Perth, Australia

³Gloucestershire Royal Hospital, UK

Combined insulin and liraglutide is associated with metabolic improvement and reduction in insulin dose in commonly prescribed insulin regimens: an ABCD Nationwide Liraglutide Audit analysis RESULTS Fig. 1. The pie chart shows the breakdown of patients by insulin regime at liraglutide initiation in terms of number of patients (%). Table 1. Baseline characteristics of patients categorised by their insulin regime at liraglutide initiation. P values: *<0.01, **<0.001, ***<0.0001 P