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Endobarrier Studies

Endobarrier is a 60cm tube-like liner made from a thin, flexible and durable impermeable polymer. It is inserted by an endoscopy and prevents food that passes through it from contacting the first two feet of small bowel intestine. In clinical trials it leads to weight loss and improved glycaemic control and may become a useful treatment option in the future.

Current research studies funded by ABCD include the multicentre REVISE-Diabesity Endobarrier study, and ABCD’s second Endobarrier study – the End-OSA study, which aims to assess the impact of weight loss due to Endobarrier in patients with diabetes and obstructive sleep apnoea. 

Pictures illustrating Endobarrier are shown below

Figure 1.  (A) The duodenal jejunal bypass liner (DJBL) and (B) a diagram of the device in situ